"Convinced myself that I need to take matters into my own hands at this point, and stop relying on others to do my dirty work for me... but I had no idea what kind of risk I was really taking. No witty banter, no final warnings -- just a ruthless preoccupation with the guilty over the innocent -- this Spider-Man is playing by a whole new set of rules."
While still a teenager, Peter Parker was bitten by a radioactive spider, which imbued him with enhanced physical traits, the ability to cling to any surface and a preternatural sixth sense warning him of danger. Armed with his trusty web-shooters, he swings across the skyline of New York battling evil-doers. Over the years, Peter's most trusted confidante has been Mary Jane Watson, with whom he was married to for many years. By day he works as a photographer at the Daily Bugle.
The Chameleon is a Russian spy and criminal who has been operating out of the United States for many years. A master of disguise, he utilizes an array of masks, and hi-tech gadgetry to completely mask his identity, making him appear as anyone he chooses to. Using this traits, he has impersonated Spider-Man on many occasions, causing the wall-crawler an insurmountable measure of grief.
Mary Jane Watson is the ultimate fun girl. She's done it all: Model, dancer, soap opera star. Mary Jane has been a close friend of Peter Parker for many years, discovering his secret identity very early on. After dating for a great number of years, Peter and M.J. eventually tied the knot. But all that ended after a reality-altering deal with Mephisto warped events, making it so that they never got together.
May Parker is the elderly widow of Ben Parker and the doting aunt of Peter Parker, aka Spider-Man. Though she has always adored her nephew, May has likewise nursed a lifelong hatred of his costumed alter ego. Though historically frail in health and seemingly always having one foot firmly planted in the grave, May Parker seems to have enjoyed renewed vitality in more recent years and even found love again in the form of her second husband, J. Jonah Jameson.
John Jameson is the son of J. Jonah Jameson as well as a former NASA astronaut and one of the last men to walk on the moon. During a lunar landing, Jameson was exposed to a red mineral, which transformed him into a werewolf known as the Man-Wolf. Jameson has since cured himself of his condition and later went on to work as a security chief for the Ravencroft Institute for the Criminally Insane.