Mesopotamia was a historic region situated within the Tigris–Euphrates river system, in modern days roughly corresponding to most of Iraq plus Kuwait, the eastern parts of Syria, Southeastern Turkey, and regions along the Turkish-Syrian and Iran–Iraq borders.
In the 1956 sci-fi/horror film The Mole People, it was believed that a culture of Sumerian albinos took to hiding in immense caverns beneath the Earth. They discovered a race of mutant mole people, which they enslaved and forced to do their bidding.