Outside the world of Star Trek, Marina also played a character named Olivia "Liv" Kohler in "The Grell" episode of The Outer Limits. In 1999, she appeared in the "The Cloister" episode of Earth: Final Conflict as Sister Margarette. She appeared in the season four episode of Stargate SG-1 entitled "Watergate" playing a Russian scientist named Doctor Svetlana Markov. In 2008, she played Attorney Barry in InAlienable and in 2009 she portrayed a character named Paxton in Annihilation Earth.
Marina Sirtis originally auditioned for the role of Tactical Officer Tasha Yar on Star Trek: The Next Generation. The part eventually went to actress Denise Crosby.
Marina Sirtis wore black contact lenses while playing Deanna Troi in both Star Trek: The Next Generation and the four Star Trek feature films she appeared in. Her character's race, Betazoids, all have black eyes.
Is best friends with Star Trek co-star Michael Dorn.