The mail boy was an unidentified youth who worked for the Umbrella Corporation. He was a member of the internal staff stationed at the top-secret underground facility known as the Hive. When the deadly T-Virus contagion was released, the site's artificial intelligence, the Red Queen, put the entire facility on lock down. All internal office areas were sealed off as halon gas containing high levels of nitrogen was pumped into each area. The mail boy was but one of many such innocent people who fell victim to the virus, and as a consequence, was resurrected as a flesh-eating zombie.
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