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| Desiree Dupree | |
| Aliases: | Derek Dupree, Jr. |
| Continuity: | American Horror Story |
| Notability: | Main character |
| Type: | Human oddity |
| Gender: | Female |
| Location: | Jupiter, Florida |
| Associations: | Fräulein Elsa's Cabinet of Curiosities |
| Relatives: | Dell Toledo [1] Angus T. Jefferson [2] |
| Status: | Alive |
| First: | "Massacres and Matinees" |
| Final: | "Curtain Call" |
| Actor: | Angela Bassett |
Desiree Dupree is a fictional entertainer and human oddity featured on the FX Network television series American Horror Story. Played by actress Angela Bassett, she appeared in season four of the show, which was billed under the subheading of "Freak Show". She was introduced in "Massacres and Matinees" and made eleven appearances in the series in total.