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| Calypso Ezili | |
| Continuity: | Marvel Universe |
| Notability: | Antagonist |
| Type: | Voodoo priestess |
| Gender: | Female |
| Race: | Human |
| Location: | Haiti |
| Status: | Deceased |
| First: | Amazing Spider-Man #209 |
| Final: | Spectacular Spider-Man #253 |
| Actor: | Ariana DeBose |
Calypso Ezili, often referred to as just Calypso, is a fictional voodoo priestess and a recurring antagonist featured in comic books published by Marvel Comics. She first appeared in The Amazing Spider-Man, Volume 1 #209 in October, 1980.