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| Alistaire Smythe | |
| Aliases: | Alistaire Alphonso Smythe Spider-Slayer |
| Continuity: | Marvel Universe |
| Notability: | Antagonist |
| Type: | Scientist |
| Gender: | Male |
| Race: | Cyborg |
| Location: | New York City, New York |
| Relatives: | Spencer Smythe (father) |
| Status: | Deceased |
| First: | Amazing Spider-Man, Vol. 1 Annual #19 |
| Final: | Superior Spider-Man #13 |