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Adreno is a fictional drug featured in the Defiance multimedia franchise. On the Defiance television series, it first appeared in episode 1x05, "A Well Respected Man".
Adreno is an addictive synthetic narcotic developed by a dealer/chemist named Meeko. Also known as The Blue Devil, it enhances the physical and mental prowess of those who imbibe it. The root substance of the drug is culled from the adrenal gland of human donors. Meeko had a bioman named Ulysses kidnap people and bring them back to his workshop so he could extract adrenal fluid from them. Two of these would-be victims were Kenya Rosewater and her employee, Tirra. Fortunately, Kenya was able to affect and escape, killing Meeko in the process.