Alpha

Alpha could refer to:
 * Alpha Flight - A Marvel Comics superhero team from Canada.
 * Alpha Quadrant - A space sector featured in the Star Trek multimedia franchise.
 * Alpha Whisperer - An antagonist featured in The Walking Dead comic series.
 * Alphas - A science fiction television series on Syfy.
 * Ceti Alpha V - A planet featured in Star Trek II: The Wrath of Khan.
 * Moonbase Alpha - A scientific research station featured in Space: 1999.